Description for KRAS-G12C
DNA KRAS-G12C
Species Homo sapiens
 KRAS-G12C identified in exosomes derived from the following tissue/cell type
Serum [Exosomes] 24398677   
 Experiment description of studies that identified KRAS-G12C in exosomes
1
Experiment ID3584
Identified moleculedsDNA-mutated
Identification methodPCR
Sanger sequencing
Whole genome shotgun sequencing
PubMed ID 24398677   
OrganismHomo sapiens
Experiment descriptionIdentification of double-stranded genomic DNA spanning all chromosomes with mutated KRAS and p53 DNA in the serum exosomes of patients with pancreatic cancer
AuthorsKahlert C, Melo SA, Protopopov A, Tang J, Seth S, Koch M, Zhang J, Weitz J, Chin L, Futreal A, Kalluri R.
Journal name J Biol Chem
Publication year2014
SampleSerum
Sample namePancreatic cancer
Molecules identified in the studydsDNA-mutated
Methods used in the studyPCR
Sanger sequencing
Whole genome shotgun sequencing
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